Yangyi (Frank) Liu
Founder, AmadeusBio.ai · AI agents that accelerate biological research
San Diego, Californialyangyilliu@gmail.comliuyangyi.comgithub.com/starryarklinkedin.com/in/yangyi-liu-a78211281
Education
2023–2025
B.S. Molecular and Cell Biology, University of California San Diego
Eleanor Roosevelt College. Conferred December 13, 2025. GPA 3.927.
Vi and Quang Pham ’06 Alumni Scholarship.Eleanor Roosevelt College Honors Project, on strigolactone synthetic biology in the Li Lab, Fall 2024.Cum laude.Provost Honors, in six quarters.
CeDiD
26TK-4GJI-YCUT, verifiable at diploma.ucsd.edu.
Experience
2026–present
Founder, AmadeusBio.ai (AmadeusBio, PBC)
Sole founder, building LLM-powered tools for biological research: Model Context Protocol (MCP) servers for PyMOL and napari, Claude Code plugins, and Molecular Animation, an open-source framework with automated tests and CI.
Jan–Dec 2025
Undergraduate researcher, Jin Lab, UC San Diego
Genes that maintain the shape of C. elegans touch-receptor neurons: genetic crosses, PCR and Sanger genotyping, fluorescence microscopy. First-author poster at the 2025 International Worm Meeting.
Winter 2025
Instructional apprentice, Biological Sciences, UC San Diego
Undergraduate teaching assistant for BIBC 102, Metabolic Biochemistry, under Professor Feng.
Jun–Aug 2024
Summer K–12 research mentor, OPALS, Institute of Engineering in Medicine, UC San Diego
Mentored high-school interns studying MSBP1 and calcium signaling in engineered yeast; they presented the work at the Biomedical Engineering Society poster expo.Poster: doi:10.6084/m9.figshare.30254713
Feb 2024–Jan 2025
Undergraduate researcher, Li Lab, UC San Diego
Strigolactone synthetic biology in a yeast and E. coli consortium, and Arabidopsis BBX31 in campesterol-producing yeast. First-author poster at the 2024 ASCB Annual Meeting.
Selected work
Oct 2026
Molecular Animation. AmadeusBio.ai · open source, Apache-2.0.
An open framework that turns a scientific brief into a molecular film with Blender. Every film comes with a production record that states, beat by beat, what is experimental and what is illustrative. The channelrhodopsin film took about two hours from idea to final render.
Jul–Sep 2026
Human-gated music agents. Personal · open source.
Claude Code skills that compose and arrange electric-guitar tablature. The model writes the tab, a validator parses and lints it, and I audition every chunk before it is accepted.
Posters
2025
Yangyi Liu, Yixiao Xiao, Ting Zhao, Seungmee Park, Yishi Jin. “LNKN-1 as a Novel Regulator of Neuronal Morphologies in C. elegans.” International Worm Meeting, 2025.
2024
Yangyi Liu, Zixu Chen, Zechun Wang, Alan R. Zhang, Ethan E. Chin, Kaibiao Wang, Veronica Gomez-Godinez, Linda Shi, Yanran Li. “Investigating the Function of Arabidopsis thaliana Transcription Factor BBX31 in Saccharomyces cerevisiae.” ASCB Annual Meeting, 2024.
Skills
- AI agents
- Agent architectures and tool use, Model Context Protocol (MCP) servers (PyMOL, napari), Claude Code skills and plugins, evals with graders, RAG, model fine-tuning
- Software and ML
- Python (NumPy, pandas, pytest), PyTorch, Hugging Face, TypeScript, React, SQL, Docker, AWS, GCP, CI/CD
- Computational biology
- AlphaFold 3, PDB/mmCIF structure analysis, PyMOL, ChimeraX, R (Seurat, Bioconductor), Scanpy, Fiji/ImageJ, statistics, Blender (Python API) for 3D visualization
- Wet lab
- Cloning, PCR and qPCR, mammalian cell culture, yeast and E. coli strain engineering, flow cytometry, protein expression and purification, Western blot, ELISA, LC-MS, fluorescence microscopy, Benchling
- Languages
- English, Mandarin (fluent), Japanese (intermediate)
Selected coursework
Bioinformatics Laboratory · Genome Diversity and Dynamics · Physics of the Cell · Biochemical Structure and Function · Metabolic Biochemistry · Recombinant DNA Techniques · Cellular Neurobiology · Genetics · Molecular Biology · Cell Biology · Calculus-Based Probability and Statistics · Phenomenology · Political Thought: Kant to Nietzsche